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Amlodipine 5mg + Atenolol 25mg Tablet
- Hypertension is not controlled by monotherapy.
- Angina pectoris and hypertension co-existing diseases.
- Post myocardial infarction (MI) patients.
- Refractory angina pectoris where nitrate therapy has failed.
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✅ Description:
- Oral treatment for chronic stable angina and hypertension.
- Additive effect with catecholamine-depleting drugs. Monitor for hypotension and bradycardia.
- Excessive BP fall is possible in the elderly. Caution in various conditions.
- Atenolol is cardioselective, and Amlodipine is a calcium-channel blocker, resulting in additive antihypertensive action.
- Avoid untreated phaeochromocytoma.
- Caution in essential hypertension, angina, post-MI, and refractory angina patients.
- Common side effects include headache, hypotension, dizziness, fatigue, muscle cramps, bradycardia, palpitations, flushing, edema, dyspnea, and dyspepsia.
- Possible interactions with various conditions and drugs.
- Avoid conditions like hypotension, bradycardia, heart block, cardiogenic shock, congestive failure, and hypersensitivity.
Safety Advices
Alcohol
UNSAFE
It is unsafe to consume alcohol with Aloten 5/25.
Pregnancy
CONSULT YOUR DOCTOR
Aloten 5/25 is considered unsafe during pregnancy due to definite evidence of risk to the developing baby. However, in life-threatening situations, a doctor may prescribe it if the benefits outweigh the potential risks. Consult your doctor.
Breastfeeding
CONSULT YOUR DOCTOR
Aloten 5/25 is probably unsafe during breastfeeding. Limited data suggests potential harm to the baby through breast milk. Consult your doctor.
Driving
UNSAFE
Aloten 5/25 may cause side effects affecting your ability to drive, such as dizziness, headaches, nausea, or tiredness. Exercise caution and avoid activities requiring mental focus.
Kidney
CAUTION
Exercise caution with Aloten 5/25 in patients with liver disease. Dose adjustment may be needed. Initiate at a lower dose in patients with liver disease and increase slowly with careful monitoring.
Liver
CAUTION
Use Aloten 5/25 with caution in patients with kidney disease. Dose adjustment may be necessary. Regular blood pressure monitoring is recommended for better dose adjustment.
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✔️ Uses of Aloten 5
Hypertension.
✔️ How does Aloten 5 work?
Aloten 5/25 is a combination of 2 medicines: Amlodipine and Atenolol, which lowers blood pressure effectively. Amlodipine is a calcium channel blocker that works by relaxing blood vessels while atenolol is a beta blocker that works specifically on the heart to slow down the heart rate. Together, they make the heart more efficient at pumping blood throughout the body.
✔️ Side Effects of Aloten 5
- Well-tolerated combination.
- Side effects may include fatigue, headache, edema, nausea, drowsiness, anxiety, and depression.
✔️ Quick Suggestions:
- Aloten 5/25 treats high blood pressure; continue even if feeling well.
- May cause dizziness; rise slowly to avoid falls.
- Do not stop suddenly; consult the doctor for proper guidance.
- Inform the doctor if pregnant or planning pregnancy.
✔️ Indications of Aloten 5
Aloten 5/25 is used for hypertension (high blood pressure), combining Amlodipine and Atenolol.
✔️ Pharmacology:
Amlodipine:
- Calcium antagonists inhibit calcium influx into vascular and cardiac muscle.
- Acts more on vascular smooth muscle, reducing peripheral vascular resistance and blood pressure.
- Reduces coronary vasoreactivity, lowering cardiac demand.
Atenolol:
- Cardio-selective beta blocker.
- Reduces blood pressure by lowering cardiac output, plasma renin activity, and sympathetic outflow.
- Reduces myocardial oxygen demand through negative inotropic and negative chronotropic effects.
✔️ Dosage & Administration:
- Recommended dosage: One tablet daily (Amlodipine 5 mg & Atenolol 50 mg) or (Amlodipine 5 mg & Atenolol 25 mg).
- Titration of dosage based on therapeutic response.
- In elderly patients, initiate therapy with ½ tablet (Amlodipine 2.5 mg & Atenolol 25 mg).
✔️ Interaction
- Amlodipine safely administered with various drugs.
- Atenolol interactions include reduced clearance of Disopyramide and potential additive negative inotropic effects.
- Atenolol has less potential for actions like decreased tissue sensitivity to insulin.
✔️ Contraindications
- Hypersensitivity to either component.
- Sinus bradycardia, second and higher degrees of heart block.
- Cardiogenic shock, hypotension, congestive heart failure, poor left ventricular function.
✔️ Pregnancy & Lactation
- Atenolol crosses the placenta and is contraindicated in pregnancy.
- Avoid during lactation.
✔️ Precautions & Warnings
- Amlodipine has been safely administered with various drugs.
- Atenolol interactions include reduced clearance of Disopyramide and potential additive negative inotropic effects.
- Atenolol has less potential for actions like decreased tissue sensitivity to insulin.
✔️ Storage Conditions
- Store in a cool dry place protected from light.
- Keep out of reach of children.
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lab tests, medicines, all possible side effects, drug interactions,
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